Collagen types I and III in giant papillae of vernal keratoconjunctivitis.
نویسندگان
چکیده
منابع مشابه
Growth factors and collagen distribution in vernal keratoconjunctivitis.
PURPOSE To study the extracellular composition of giant papillae in vernal keratoconjunctivitis (VKC) and the expression of growth factors that may stimulate fibrosis. METHODS Upper conjunctival specimens were obtained by biopsy in 9 patients affected by active tarsal VKC (14 eyes) and 10 normal control subjects. Immunohistochemistry was performed on tissue sections using monoclonal antibodie...
متن کاملChemokine receptor gene expression in giant papillae of atopic keratoconjunctivitis.
PURPOSE Major chemokine receptors in the giant papillae of atopic keratoconjunctivitis (AKC) have yet to be determined. We evaluated chemokine receptor genes and their ligand expressions in upper tarsal conjunctival giant papillae of AKC with atopic dermatitis and/or asthma. METHODS CC, CXC, and CX3C chemokine receptor (R) gene expression levels in giant papillae of five clinically active AKC...
متن کاملVernal keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a chronic allergic conjunctivitis that is most often seen in young, males. Although most types of allergic conjunctivitis do not affect vision, VKC is unusual in that damage to the cornea from the condition can result in vision loss. Although it is typically seasonal, year-round symptoms can be seen, which can lead to uncertain diagnoses being made. Although...
متن کاملHigh level of Fc epsilon receptor I-bindable immunoglobulin E in the tear fluid and increased immunoglobulin E-saturated cells in the giant papillae of vernal keratoconjunctivitis patients.
PURPOSE To investigate the concentrations of Fc epsilon receptor I (Fc epsilon RI)-bindable immunoglobulin E (IgE) in the tear fluid and the proportion of IgE-saturated cells among Fc epsilon RI-positive cells in giant papillae from vernal keratoconjunctivitis (VKC) patients. METHODS The tear fluids and giant papillae were obtained from 8 VKC patients with their informed consent. To detect th...
متن کاملManagement of Vernal Keratoconjunctivitis
Vernal keratoconjunctivitis (VKC) is a relatively rare, chronic form of ocular allergy that can potentially cause severe visual complications. Affecting mainly children and young adults, it is an IgE- and T cell-mediated disease, leading to a chronic inflammation in which eosinophil, lymphocyte and structural cell activation are involved. Treatment of VKC requires a multiple approach that inclu...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1995
ISSN: 0007-1161
DOI: 10.1136/bjo.79.5.482